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    <loc>https://www.imicrobes.com/blog/bio-acrylic-acid-scale-up</loc>
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    <lastmod>2025-09-09</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - iMicrobes produces 100% bio-based acrylic acid through its scaled-up bioprocess - Make it stand out</image:title>
      <image:caption>Scaled-up manufacturing of iMicrobes bio-based acrylic acid at IBRL. Credit: Taylor Meredith.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - iMicrobes produces 100% bio-based acrylic acid through its scaled-up bioprocess - Make it stand out</image:title>
      <image:caption>100% bio-based acrylic acid. Credit: iMicrobes.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - iMicrobes produces 100% bio-based acrylic acid through its scaled-up bioprocess - Make it stand out</image:title>
      <image:caption>Credit: World Bio Markets.</image:caption>
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    <lastmod>2025-07-11</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - What it takes to commercialize bio-based solutions today - Make it stand out</image:title>
      <image:caption>Credit: WBM</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - What it takes to commercialize bio-based solutions today - Make it stand out</image:title>
      <image:caption>iMicrobes scale-up milestones.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - What it takes to commercialize bio-based solutions today - Make it stand out</image:title>
      <image:caption>Credit: WBM25</image:caption>
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    <lastmod>2025-05-13</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - How to design a biomanufacturing process for success - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - How to design a biomanufacturing process for success</image:title>
      <image:caption>Credit: Evonik</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - How to design a biomanufacturing process for success - Make it stand out</image:title>
      <image:caption>iMicrobes biomanufacturing process</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - How to design a biomanufacturing process for success - Make it stand out</image:title>
      <image:caption>Credit: iMicrobes</image:caption>
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    <loc>https://www.imicrobes.com/blog/new-markets-for-ethanol-production</loc>
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    <lastmod>2025-02-15</lastmod>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5f1e426a68df2a40e2e0ef49/bb9b001b-70ff-4078-9387-af926705c4d3/paint+picturepexels-2468922-4089071.jpg</image:loc>
      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Unlock new markets for your ethanol production</image:title>
      <image:caption>Consumers &amp; supply chains are moving toward sustainability 55% of consumers will pay more for eco-friendly brands. (Source BusinessDIT) 92% of customers trust environmentally conscious companies. (Source BusinessDIT ) Sustainable markets are growing 2.7x faster than their non-sustainable counterparts. (Source: theroundup.org) Demand for bio-based chemicals is soaring Acrylic Acid: Essential for paints, coatings, adhesives, and personal care products. Acrylonitrile: A key precursor for carbon fiber, used in automotive, aerospace, and high-performance materials. Domestic supply chains need reliable biobased feedstocks Paints and coatings manufacturers worry about supply dominance by large petrochemical players. Cosmetics and personal care brands are actively seeking sustainable, biobased solutions.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Unlock new markets for your ethanol production - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f1e426a68df2a40e2e0ef49/351ac405-0931-4721-887c-cbbbca938730/iMicrobes+Sample.jpg</image:loc>
      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Unlock new markets for your ethanol production</image:title>
      <image:caption>Key milestones: Scaling up for commercial success iMicrobes has achieved major milestones in scaling ethanol-based biomanufacturing, bringing us closer to full commercialization. In August 2024, we successfully produced 10 kg+ of polymer per run while scaling fermentation to 1,500L and refining purification processes. This progress was bolstered by a DoD award to support our first commercial facility and a BioMADE grant to accelerate our second product, sustainable carbon fiber. By November, our fermentations demonstrated excellent alignment between bench-scale and pilot-scale results, yielding another 10 kg+ of polymer with improved process parameters. In January 2025, we achieved kg-scale polymer purification, allowing us to begin sharing samples with partners and setting the stage for acrylic acid conversion in Q1 and Q2. With a 60% cost reduction since early 2024, iMicrobes is rapidly advancing toward cost-competitive, scalable biomanufacturing solutions.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Unlock new markets for your ethanol production - Make it stand out</image:title>
      <image:caption>iMicrobes combines biology and chemistry to create drop-in replacement chemicals from ethanol.</image:caption>
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    <lastmod>2025-02-07</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Microbe mission possible: Noah Helman discusses iMicrobes quest to turn waste into wealth on the Grow Everything Podcast - Make it stand out</image:title>
      <image:caption>Credit: Grow Everything</image:caption>
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    <lastmod>2025-02-14</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Industrial Microbes&amp;nbsp;announces seed round funding - Make it stand out</image:title>
      <image:caption>iMicrobes leadership team: Dr. Elizabeth Clarke, CTO, Dr. Derek Greenfield, President, Dr. Noah Helman, CEO.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Industrial Microbes&amp;nbsp;announces seed round funding</image:title>
      <image:caption>iMicrobes is scaling up its fermentation to produce more than 10 kg of product per run in a pilot bioreactor, and accelerate the commercialization of its bio-based acrylic acid production platform. Acrylic acid, a versatile chemical used in products ranging from paints to diapers, has traditionally been sourced from petrochemicals.  iMicrobes has successfully developed two distinct pathways for producing bio-based acrylic using methane and ethanol as feedstocks. Methane, a potent greenhouse gas, is sourced from industrial by-products and agricultural residues, transforming a harmful waste stream into a valuable resource. Ethanol, widely used as a biofuel, can now play a growing role in producing sustainable materials. Using ethanol to support domestic biomanufacturing can strengthen domestic supply chains for critical materials.</image:caption>
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    <lastmod>2024-10-17</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Scaling up biobased chemicals made from ethanol - Ethanol: A key feedstock: While ethanol has long been used for food, animal feed, and fuel, Industrial Microbes is pioneering its use as a chemical feedstock. The company has engineered E. coli to produce poly-3HP through fermentation, where the polymer can accumulate to over 80% of the cell's weight. After fermentation, the process uses thermal decomposition to break down the polymer into acrylic acid, which is then purified via simple distillation. This streamlined process cuts down on unit operations, reducing both complexity and costs while leveraging ethanol as a renewable feedstock. The result is a cost-effective, scalable method for producing high-purity biobased acrylic acid.</image:title>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Scaling up biobased chemicals made from ethanol - Scaling up: Supported by the Department of Energy and other partners, the team has scaled their operations from lab tests to larger fermentation runs, with a focus on maintaining high yields and reducing costs (check out our blog to know more).</image:title>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5f1e426a68df2a40e2e0ef49/5302041c-8802-485b-9d0c-f422a2ed1241/coloc.jpg</image:loc>
      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Scaling up biobased chemicals made from ethanol - Looking ahead: Collaboration opportunities Industrial Microbes is eager to work with ethanol producers and industry stakeholders to explore partnerships, co-location opportunities, and integration strategies. These partnerships will help further reduce production costs and bring sustainable, biobased materials to market faster. If you’re interested in learning more or exploring collaboration opportunities, reach out!</image:title>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Scaling up biobased chemicals made from ethanol - Make it stand out</image:title>
      <image:caption>Industrial Microbes at Bio Innovations Midwest</image:caption>
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    <loc>https://www.imicrobes.com/blog/agile-biofoundry-abpdu-scale-up</loc>
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    <priority>0.5</priority>
    <lastmod>2024-10-08</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Department of Energy's Agile BioFoundry and ABPDU Partner with Industrial Microbes to successfully scale up bio-based process. - Make it stand out</image:title>
      <image:caption>The Industrial Microbes team collaborated with researchers at the ABPDU, a facility that specializes in scaling up bio-based processes.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - Department of Energy's Agile BioFoundry and ABPDU Partner with Industrial Microbes to successfully scale up bio-based process. - Make it stand out</image:title>
      <image:caption>Industrial Microbes process converts ethanol and waste carbon dioxide into bio-based acrylic acid.</image:caption>
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    <loc>https://www.imicrobes.com/blog/imicrobes-partners-with-ifab-tech-hub</loc>
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    <lastmod>2024-08-30</lastmod>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - iFAB Tech Hub grows net-zero industrial chemical partnerships with iMicrobes, champions bioeconomy. - Make it stand out</image:title>
      <image:caption>From left: Hana Ostrander, IBRL junior pilot plant specialist, and Amanda Beverly, director of fermentation for iMicrobes.</image:caption>
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      <image:title>Blog | Biotech, net-zero production, and climate insights | iMicrobes - iFAB Tech Hub grows net-zero industrial chemical partnerships with iMicrobes, champions bioeconomy. - “With the support of the landmark EDA grant, iFAB is building a robust biomanufacturing ecosystem across Central Illinois that empowers companies to bring their bioinnovations from the laboratory to full-scale production,” Conerty said. “Our goal is to make Central Illinois the go-to destination for enterprises turning scientific advancements into real-world, eco-friendly solutions that redefine industrial chemistry.”</image:title>
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